A novel tea-bag methodology for enzymatic resolutions of α-amino acid derivatives in reverse micellar media

Article abstract of DOI:10.1080/00397919408010223

A novel tea bag methodology for resolution of methyl esters of N-acetyl- α-amino acids in reverse micellar medium of bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) in isooctane-chloroform using immobilized enzymes or microbial cells is presented. The methodology effectively solves the problems of substrate solubility, product separation and surfactant recycling and provides products in high yields (80 to 90%) and excellent optical purities (% ee 97 to >99%).

Full text of DOI:10.1080/00397919408010223

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Novel Tea-Bag Methodology
for Enzymatic Resolutions of
α-Amino Acid Derivatives in
Reverse Micellar Media
U. T. Bhalerao a , A. Sreenivas Rao a & N. W.
Fadnavis a
a Indian Institute of Chemical Technology ,
Hyderabad, 500 007, India
Published online: 23 Sep 2006.
To cite this article: U. T. Bhalerao , A. Sreenivas Rao & N. W. Fadnavis (1994) A
Novel Tea-Bag Methodology for Enzymatic Resolutions of α-Amino Acid Derivatives
in Reverse Micellar Media, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 24:15, 2109-2118, DOI:
10.1080/00397919408010223
To link to this article: http://dx.doi.org/10.1080/00397919408010223
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