Tetrahedron Asymmetry p. 2381 - 2386 (1996)
Update date:2022-08-28
Topics:
Nakano, Hiroto
Iwasa, Kazuto
Okuyama, Yuko
Hongo, Hiroshi
The lipase-catalyzed asymmetric resolution of 2-azabicyclo[2.2.1]hept-5-en-3-ones is reported; non-racemic chiral 2-azabicyclo[2.2.1]hept-5-en-3-ones were obtained conveniently by lipase-catalyzed enantioselective transesterification or hydrolysis of N-hydroxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one or N-acyloxymethyl-2-azabicyclo[2.2.1]hept-5-en-3-one.
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