A novel indium-catalyzed sonogashira coupling reaction, effected in the absence of a copper salt, phosphine ligand and palladium

Article abstract of DOI:10.1055/s-2005-918948

An efficient copper-, phosphine ligand- and palladium-free indium-catalyzed Sonogashira coupling reaction has been developed in the presence of 1 mol% indium trichloride. Coupling of various aryl halides with terminal alkynes afforded the corresponding aryl alkynes in moderate to excellent yields. Georg Thieme Verlag Stuttgart.