Journal of Organic Chemistry p. 3674 - 3680 (1987)
Update date:2022-08-29
Topics:
Burns, Timothy P.
Rieke, Reuben D.
A method for producing highly reactive magnesium slurries is presented, along with a brief comparison to other methods of activation.Reactions of the activated magnesium with a variety of functional groups are examined, including ethers, tosylates, and nitriles.Attempts were made to form Grignard reagents which contained ketone, ester, and nitrile functionality.The Grignard reagent from 8-bromooctane-1-nitrile was succesfully prepared in moderate yield.
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