Tetrahedron Letters p. 4907 - 4910 (1983)
Update date:2022-08-10
Topics:
Seyferth, Dietmar
Weinstein, Robert M.
Wang, Wei-Liang
Hui, Richard C.
Aldehydes be may acylated to give R'CH(OH)C(O)R in good yield by the RLi/CO in situ procedure at very low temperatures.Examples are given of ketone acylations which demonstrate the advantages of 1:1 RLi/substrate stoichiometry and the use of lower (-135 deg C) temperature.
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Doi:10.1007/BF02853948
()Doi:10.1016/S0040-4039(01)93306-4
(1964)Doi:10.1039/DT9930002797
(1993)Doi:10.1080/00397919808004950
(1998)Doi:10.1016/j.cclet.2021.04.048
(2021)Doi:10.1055/s-0035-1562116
(2016)
