A Grignard-Type Addition of Allyl Unit to Aldehydes by Using Bismuth and Bismuth Salt

Article abstract of DOI:10.1246/bcsj.63.1738

In the presence of metallic bismuth, bismuth(III) chloride-metallic zinc, or bismuth(III) chloride-metallic iron, allylic halides have been found to react with aldehydes under mild conditions to give the corresponding homoallylic alcohols in high yields with high chemo-, regio-, and stereoselectivity.Allylic halides have been also found to react with aldehydes at room temperature in tetrahydrofuran-water by using bismuth(III) chloride-metallic aluminium to afford the expected homoallylic alcohols in high yields.