A CATALYTIC ROLE OF Cu(II) FOR CONJUGATE ADDITION OF GRIGNARD REAGENTS. A COMPLETELY DIFFERENT BEHAVIOR FROM ORGANOCUPRATES

Article abstract of DOI:10.1016/S0040-4039(00)88514-7

Different from lithium dialkycuprates, Cu(II) catalyzed conjugate addition of Grignard reagents to allylic esters of α,β-unsaturated carboxylates has been effected in the presence of TMS-Cl, and the resulting allyl silyl keteneacetals further undergo rearrangement to afford 2-allyl 3-alkyl carboxylic acids in good yields.