Tetrahedron Letters p. 8679 - 8683 (1999)
Update date:2022-08-11
Topics:
Aftab, Tajassus
Carter, Christabel
Hart, Jennifer
Nelson, Adam
Diastereomerically pure 1,3-diols were converted into the corresponding orthoesters and reacted with acetyl bromide to give bromoacetates with inversion of configuration at a benzylic position. Methanolysis and cyclisation gave diastereomerically pure 2,4-disubstituted oxetanes.
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