Oxidative Esterification of Primary Alcohols by NaBrO3/NaHSO3 Reagent in Aqueous Medium

Article abstract of DOI:10.1246/cl.1995.871

NaBrO3 combined with NaHSO3 was found to be an efficent reagent for the oxidative esterification of primary alcohols.Thus, a variety of esters was prepared from primary alcohols, aldehydes, and acetals in aqueous medium under mild conditions.Treatment of α,ω-diols with NaBrO3/NaHSO3 reagent afforded the corresponding lactones and/or dicarboxylic acids in fair yields.