Product Enantioselectivity of the Microsomal and Cytosolic Epoxide Hydrolase catalysed Hydrolysis of meso Epoxides

DOI: 10.1039/c39890001170

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1170 - 1171 (1989)

Update date:2022-08-11

Topics:

Authors:

Bellucci, Giuseppe

Capitani, Isabella

Chiappe, Cinzia

Marioni, Franco

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39890001170

1,2-Epoxycycloalkanes from C5 to C8 and cis-stilbene oxide are respectively hydrolysed to the corresponding (-)-(R,R)-trans-diols and to (+)-(R,R)-1,2-diphenylethane-1,2-diol by both the microsomal and the cytosolic epoxide hydrolase of rabbit liver, the former enzyme being more active and giving higher enantiomeric excesses.

Full text of DOI:10.1039/c39890001170

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,2R)-TRANS-1,2-CYCLOHEXANEDIOL

Cas No:1072-86-2

R&D Labs maybe for 1072-86-2

Shanghai Hanhong Scientific Co.,Ltd.

website:http://www.chemvia.com

Contact:+86-21-64541543,54280654,13918533501

Address:Jiachuan Road 245
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province
Pale Palm Imex

Contact:+36(21)2523420

Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
NanJing Rate Biochemicals CO., LTD

Contact:+86-25-84931986

Address:NO. 1 Hongjing Road,Jiangning Science Park,Nanjing,China
Chinapeptides Co,. Ltd

Contact:+86-021-50792271

Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202

Relevant to this article

Is pseudorotation the operational pathway for bond shifting within [8]annulenes? Probe of planarization requirements by 1,3-annulation of the cyclooctatetraene ring. Kinetic analysis of racemization and 2-D NMR quantitation of π-Bond alternation and ring inversion as a function of polymethylene chain length

Doi:10.1021/ja00157a038
(1990)
Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states

Doi:10.1021/ja1096539
(2011)
Visible light-induced intramolecular dearomative cyclization of α-bromo-N-benzyl-alkylamides: Efficient construction of 2-azaspiro[4.5]decanes

Doi:10.1039/c5cc09726f
(2016)
One-Shot Double Amination of Sondheimer-Wong Diynes: Synthesis of Photoluminescent Dinaphthopentalenes

Doi:10.1021/acs.orglett.5b01293
(2015)
Microwave-assisted one-pot synthesis of (aminoalkyl)naphthols and (aminoalkyl)quinolinols by using ammonium carbamate or ammonium hydrogen carbonate as solid ammonia source

Doi:10.1055/s-0028-1083347
(2009)
Fully meta-Substituted 4,4′-Biphenyldicarboxylate-Based Metal–Organic Frameworks: Synthesis, Structures, and Catalytic Activities

Doi:10.1002/ejic.201601242
(2017)

Article Doi