Product Enantioselectivity of the Microsomal and Cytosolic Epoxide Hydrolase catalysed Hydrolysis of meso Epoxides

DOI: 10.1039/c39890001170

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1170 - 1171 (1989)

Update date:2022-08-11

Topics:

Authors:

Bellucci, Giuseppe

Capitani, Isabella

Chiappe, Cinzia

Marioni, Franco

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39890001170

1,2-Epoxycycloalkanes from C5 to C8 and cis-stilbene oxide are respectively hydrolysed to the corresponding (-)-(R,R)-trans-diols and to (+)-(R,R)-1,2-diphenylethane-1,2-diol by both the microsomal and the cytosolic epoxide hydrolase of rabbit liver, the former enzyme being more active and giving higher enantiomeric excesses.

Full text of DOI:10.1039/c39890001170

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,2R)-TRANS-1,2-CYCLOHEXANEDIOL

Cas No:1072-86-2

R&D Labs maybe for 1072-86-2

Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
Engineering Research Center of Pesticide, Heilongjiang Province

Contact:+86-451-86609001

Address:No.74 of Xuefu Road, Nangang District,
Shenyang NovPharm Technology Co., Ltd.

Contact:.+86-24-24165786

Address:Room 306, Hongjin Mansion, No. 36-1, Wanliutang Rd., Shenhe District, Shenyang, Liaoning, P.R.C.
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Wuhan Biet Co., Ltd

website:http://www.biet.com.cn/

Contact:+86-27-8369 8488

Address:No. 6, Building 21, China Merchants Fanwang, Sixin North Road, Hanyang District, Wuhan City, Hubei Province

Relevant to this article

Is pseudorotation the operational pathway for bond shifting within [8]annulenes? Probe of planarization requirements by 1,3-annulation of the cyclooctatetraene ring. Kinetic analysis of racemization and 2-D NMR quantitation of π-Bond alternation and ring inversion as a function of polymethylene chain length

Doi:10.1021/ja00157a038
(1990)
Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states

Doi:10.1021/ja1096539
(2011)
Visible light-induced intramolecular dearomative cyclization of α-bromo-N-benzyl-alkylamides: Efficient construction of 2-azaspiro[4.5]decanes

Doi:10.1039/c5cc09726f
(2016)
One-Shot Double Amination of Sondheimer-Wong Diynes: Synthesis of Photoluminescent Dinaphthopentalenes

Doi:10.1021/acs.orglett.5b01293
(2015)
Microwave-assisted one-pot synthesis of (aminoalkyl)naphthols and (aminoalkyl)quinolinols by using ammonium carbamate or ammonium hydrogen carbonate as solid ammonia source

Doi:10.1055/s-0028-1083347
(2009)
Fully meta-Substituted 4,4′-Biphenyldicarboxylate-Based Metal–Organic Frameworks: Synthesis, Structures, and Catalytic Activities

Doi:10.1002/ejic.201601242
(2017)

Article Doi