Simple and convenient method for the synthesis of Δ9(11)-3-hydroxy, Δ1,4- and Δ1,4,9(11)-3-ketosteroids by selective dehydrogenation of 3-hydroxy-12-ketosteroids

Article abstract of DOI:10.1246/cl.1998.1207

Hecogenin can be selectively dehydrogenated to the corresponding Δ⁹⁽¹¹⁾-3-hydroxysteroid, Δ^1,4- and Δ^1,4,9(11)-ketosteroids by the treatment of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) with a variety of solvents.