Biomimetic total synthesis of polycitrin A

Article abstract of DOI:10.1016/0040-4020(95)00568-S

The synthesis of the marine alkaloid polycitrin A (1a) is described. The synthesis is based on the formation of 3,4-bisarylpyrrole-2,5-dicarboxylic acids from 3-arylpyruvic acids by oxidative coupling and consecutive pyrrole ring formation. The pyrrole di