Synthetic Communications p. 1253 - 1260 (1994)
Update date:2022-08-10
Topics:
Berlan
Delmas
Duee
Luche
Vuiglio
Deprotonation-alkylation of n-alkyl cyanides can be readily effected by an alkyl halide in the presence of sodium in a one pot procedure. Yields are generally better than in the usual methods, and the overall reaction conditions have important advantages
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