Journal of the Chemical Society - Faraday Transactions p. 803 - 810 (1993)
Update date:2022-08-10
Topics:
Land, Edward J.
The stoichiometry of the reactions of semiquinones resulting from the one-electron oxidation of various dihydroxybenzenes is examined.It is verified that the semiquinones of hydroquinone and catechol disproportionate completely to give p-benzoquinone and o-benzoquinone, respectively.With resorcinol, however, the corresponding semioxidised radical reaction is different, giving unstable dimers which subsequently rearrange to tetrahydroxybiphenyls.The usefulness of catechol one-electron oxidation followed by o-semiquinone disproportionation as a means of preparing biologically important unstable o-quinones is exemplified by three new examples: (1) The o-quinone of oestradiol which may have melanocytotoxic properties; (2) the o-quinone of salsolinol whose oxidative metabolites may be responsible for neuronal damage in alcoholism and (3) o-quinone of tetrahydropapaveroline whose oxidative metabolism may play a role in both alcohol addiction and Parkinson's disease.
View MoreContact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.
Contact:+86-750-2881198
Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
website:http://www.joyochem.com
Contact:0531-82687998
Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
SHIJIAZHUANG CHENSHI IMPORT AND EXPORT CO.,LTD
Contact:+86-311-89871056
Address:RM2017 BUILDING CTIANSHAN GALAXY PLAZA,NO168 CHANGJIANG ROAD,GAOXIN DISTRICT,SHIJIAZHUANG CITY, HEBEI,CHINA
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Doi:10.1016/j.electacta.2018.03.103
(2018)Doi:10.1021/jo061243y
(2006)Doi:10.1016/S0022-328X(96)06496-0
(1997)Doi:10.1039/c39850000788
(1985)Doi:10.1039/c39870000637
(1987)Doi:10.1139/v02-143
(2002)
