Tetrahedron Letters p. 2673 - 2676 (1990)
Update date:2022-08-11
Topics:
Toyokuni, Tatsushi
Dean, Barbara
Hakomori, Sen-Itiroh
Monomer, dimer, and trimer of Tn antigen (GalNAcα1-O-Ser) were coupled to L-lysyllysine to construct multivalent and clustering structures of Tn antigen.The method has made it possible to provide pertinent carbohydrate antigens for the development of synthetic vaccines against tumors.
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