A Comparative Investigation of the Reactions of α-Metallomethyl Isocyanides with α,β-Unsaturated Ketones

DOI: 10.1055/s-1987-27957

Source and publish data:

Synthesis p. 391 - 393 (1987)

Update date:2022-08-16

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Authors:

Westling, Mark

Livinghouse, Tom

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Article abstract of DOI:10.1055/s-1987-27957

The nucleophilic addition of lithiomethyl isocyanide to representative α,β-unsaturated ketones has been examined.The ratio of 1,2- to 1,4-addition is dependent upon the inclusion of ligating cosolvents.In addition, the reactions of alternative α-metallomethyl isocyanides with α,β-unsaturated ketones have been studied.

Full text of DOI:10.1055/s-1987-27957

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