An Anomalous Eschweiler-Clarke Reaction

DOI: 10.1016/S0040-4039(00)79393-2

Source and publish data:

Tetrahedron Letters p. 3847 - 3848 (1991)

Update date:2022-08-24

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Authors:

Rahal, Said

Badache, Leila

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Article abstract of DOI:10.1016/S0040-4039(00)79393-2

Reaction of β-alanine 1 with formaldehyde in the presence of formic acid under Eschweiler-Clarke conditions yields the corresponding betaine 3 instead of the expected N,N-dimethyl β-alanine 2

Full text of DOI:10.1016/S0040-4039(00)79393-2

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