A New and Efficient Synthesis of Trifluoromethyl Ketones from Carboxylic Acids. Part I.

DOI: 10.1016/0040-4020(95)00006-T

Source and publish data:

Tetrahedron p. 2573 - 2584 (1995)

Update date:2022-08-29

Topics:

Authors:

Boivin, Jean

El Kaim, Laurent

Zard, Samir Z.

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Article abstract of DOI:10.1016/0040-4020(95)00006-T

Trifluoromethyl ketones can be prepared in good yield from primary carboxylic acid chlorides by reaction with pyridine and trifluoroacetic anhydride followed by aqueous work up.

Full text of DOI:10.1016/0040-4020(95)00006-T

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