PALMILYCORINE AND LYCORISIDE: ACYLOXY AND ACYLGLUCOSYLOXY ALKALOIDS FROM CRINUM ASIATICUM

Article abstract of DOI:10.1016/S0031-9422(00)80698-6

Two new types of alkaloidal conjugates, a C16-acyloxy derivative, named palmilycorine, and an acylglucosyloxy derivative, named lycoriside, were isolated from the fruits of Crinum asiaticum.The presence of these compounds was also detected in the fleshy scale leaves and in roots of these species.The structures of the two compounds were established as 1-O-palmitoyllicorine (1) and lycorine-1-O-(6'-O-palmitoyl-β-D-glucopyranoside) (2), respectively, on the basis of chemical transformation and comprehensive spectral evidence.The biological effects of the alkaloids were evaluated. Key Word Index - Crinum asiaticum; Amaryllidaceae; fruits; alkaloids; alkaloidal conjugates; palmilycorine, 1-O-palmitoyllicorine; lycoriside, lycorine-1-O-(6'-O-palmitoyl-β-D-glucopyranoside); lycorine-1-O-β-D-glucoside; promoters of cell viability, cell growth and root growth.