Synthesis of Methylthio- and Aminoalkylidene Derivatives of Meldrum's Acid

DOI: 10.1055/s-1987-27975

Source and publish data:

Synthesis p. 480 - 481 (1987)

Update date:2022-08-16

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Authors:

Huang, Xiang

Chen, Bang-chi

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Article abstract of DOI:10.1055/s-1987-27975

Reaction of Grignard reagents with isopropylidene bis(methylthio)methylenemalonate (1) resulted in conjugate addition to give an intermediate 2, which could either be hydrolyzed to an isopropylidene (1-methylthioalkylidene)malonate 3 or reacted with ammon

Full text of DOI:10.1055/s-1987-27975

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