Spruce budworm (Choristoneura fumiferana) antifeedants 4. Synthesis of specionin and biological studies

Article abstract of DOI:10.1139/v94-271

Specionin (1) was synthesized in seven steps from aucubin (2), an abundant iridoid form aucuba japonica. In a 'no-choice,' bioassay, specionin and several of its derivatives showed only modest antifeedant activity against the spruce budworm, while other derivatives were devoid of activity.