Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

DOI: 10.1016/j.ejmech.2020.113122

Source and publish data:

European Journal of Medicinal Chemistry (2021)

Update date:2022-08-30

Topics:

Authors:

Spanò, Virginia

Barreca, Marilia

Rocca, Roberta

Bortolozzi, Roberta

Bai, Ruoli

Carbone, Anna

Raimondi, Maria Valeria

Piccionello, Antonio Palumbo

Montalbano, Alessandra

Alcaro, Stefano

Hamel, Ernest

Viola, Giampietro

Barraja, Paola

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Article abstract of DOI:10.1016/j.ejmech.2020.113122

A series of [1,3]thiazolo[4,5-e]isoindoles has been synthesized through a versatile and high yielding multistep sequence. Evaluation of the antiproliferative activity of the new compounds on the full NCI human tumor cell line panel highlighted several com

Full text of DOI:10.1016/j.ejmech.2020.113122

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Product name:2-(p-methoxybenzyl)-2,5,6,7-tetrahydro-4H-isoindol-4-one

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