Novel synthesis and enzymatic resolution of (±)-2,3-epoxy propyl esters

Article abstract of DOI:10.1080/00397919908086413

A novel method of synthesizing glycidyl esters (±) -2,3-epoxy propyl esters has been developed involving reaction of epichlorohydrin with sodium salt of carboxylic acids in the presence of 15-crown-5 as catalyst with excellent yields. Enzymatic resolution of these glycidyl esters by lipasePS- C has been achieved with remarkable substrate selectivity.

Full text of DOI:10.1080/00397919908086413

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Synthetic Communications: An
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Novel Synthesis And Enzymatic
Resolution of (±) -2,3 - Epoxy Propyl
Esters
a
a
Ranjeet V. Nair , Prashant N. Patil & Manikrao M.
a
Salunkhe
a
Department of Chemistry, The Institute of Science, 15-
Madam Cama Road, Mumbai, 400032, India
Version of record first published: 25 Sep 2007.
To cite this article: Ranjeet V. Nair , Prashant N. Patil & Manikrao M. Salunkhe (1999):
Novel Synthesis And Enzymatic Resolution of (±) -2,3 - Epoxy Propyl Esters, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic Organic
Chemistry, 29:15, 2559-2566
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