Journal of Medicinal Chemistry p. 2132 - 2136 (1988)
Update date:2022-08-11
Topics:
Venuti, Michael C.
Loe, Brad E.
Jones, Gordon H.
Young, John M.
A series of 2,3-(alkylidenedioxy)naphthalene analogues (5a-p) of lonapalene (RS-43179,1), a 5-lipoxygenase inhibitor currently under clinical investigation for the treatment of psoriasis, has been prepared and evaluated for topical inhibitory activity aga
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