A short enantioselective formal synthesis of methyl (S)-(-)-6,8-dihydroxyoctanoate: A key intermediate for the synthesis of R-(+)-α-lipoic acid

DOI: 10.1055/s-1996-4380

Source and publish data:

Synthesis p. 1289 - 1290 (1996)

Update date:2022-08-30

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Authors:

Bezbarua, Maitreyee

Saikia, Anil K.

Barua, Nabin C.

Kalita, Dipak

Ghosh, Anil C.

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Article abstract of DOI:10.1055/s-1996-4380

A short enantioselective formal synthesis of methyl (S)-(-)-6,8-dihydroxyoctanoate starting from readily available 2-nitrocyclohexanone using a novel retro-Henry reaction is described.

Full text of DOI:10.1055/s-1996-4380

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