Rapid and highly selective cleavage of ribonucleoside 2',3'-cyclic monophosphates by dinuclear Cu(II) complexes

DOI: 10.1002/anie.199726781

Source and publish data:

Angewandte Chemie - International Edition in English p. 2678 - 2680 (1997)

Update date:2022-08-11

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Authors:

Liu Liu

Luo Luo

Hamilton

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Article abstract of DOI:10.1002/anie.199726781

Two characteristics that never before appeared together are combined in complexes 1 and 2, which show high activity and high selectivity in the hydrolysis of cyclic nucleoside 2',3'-monophosphates as model compounds for RNA. In the case of 1 the regioselectivity is exceptional, and, in the case of 2, the base selectivity.

Full text of DOI:10.1002/anie.199726781

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