NUCLEOPHILIC SUBSTITUTION OF α-ALLENIC ALCOHOLS VIA THE MURAHASHI METHOD: 1,3-DIENES SYNTHESIS.

DOI: 10.1016/S0040-4039(00)82022-5

Source and publish data:

Tetrahedron Letters p. 1701 - 1704 (1988)

Update date:2022-08-16

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Authors:

Fan, Changlie

Cazes, Bernard

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Article abstract of DOI:10.1016/S0040-4039(00)82022-5

The alkylation of α-allenic alcohols 1 by the Murahashi procedure leads to 1,3-dienes 4.This process allows the direct nucleophilic substitution of labile or hindered α-allenic alcohols by organolithium reagents.

Full text of DOI:10.1016/S0040-4039(00)82022-5

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