Tetrahedron Letters p. 1947 - 1950 (1988)
Update date:2022-08-02
Topics:
Takasu, Mayumi
Naruse, Yuji
Yamamoto, Hisashi
A method is described for regioselective monoprotection of 1,n-diols.The new process depends on regioselective cleavage of orthoester, which is prepared in situ from 1,n-diols and trialkylorthoesters.The produced mono-acetal is useful in subsequent steps as a normal acetal type protecting group.
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