6622
linkers are suitable for the anchoring of amines, phenols and alcohols, allowing the construction
of both peptide and organic combinatorial libraries in a bi-directional fashion. The strategy
should expand the utility of Merri®eld resin and increase the sophistication of solid-phase
synthesis. Currently, we are in the process of using this protocol in the combinatorial synthesis of
radiosumin libraries and those results will be reported in due course.
Acknowledgements
The authors are grateful to the National Science Council, ROC, for the ®nancial support (NSC
88-2113-M-008-005) of this work.
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