Journal of the Chemical Society. Perkin transactions I p. 1313 - 1318 (1993)
Update date:2022-08-17
Topics:
Cooper, Jeremy
Gallagher, Peter T.
Knight, David W.
Baker's yeast reduction of the β-oxo proline derivative 5 leads to the cis-hydroxy ester 6 and thence to (+)-cis-(2R,3S)-3-hydroxyproline 7, with >90percent enantiomeric enrichment.Subsequent one-carbon homologation leads to the (-)-Geissman-Waiss lactone
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