Medicinal Chemistry Research p. 143 - 157 (2005)
Update date:2022-07-31
Topics:
Vanden Eynde, Jean Jacques
Mayence, Annie
Johnson, Melissa T.
Huang, Tien L.
Collins, Margaret S.
Rebholz, Sandra
Walzer, Peter D.
Cushion, Melanie T.
Donkor, Isaac O.
Among a library of 17 bisbenzamidines connected with various linkers, compounds with a flexible pentanediamide (10) or hexanediamide (12) linker were the most potent derivatives against rat Pneumocystis carinii (IC50 values of 3 and 2 nM, respe
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