Journal of Organic Chemistry p. 1143 - 1145 (1991)
Update date:2022-08-28
Topics:
Davis, Franklin A.
Kumar, Anil
Chen, Bang-Chi
A highly efficient procedure for the preparation of rhodomycinone 1 AB synthons (-)-2a and (+)-2b in high enantiomeric purity (93-4percent ee) and good yield is described.This method involves asymmetric oxidation of the lithium enolate of 2-ethyl-5,8-dimethoxy-1-tetralone (4) with (+)-<(8,8-dimethoxycamphoryl)sulfonyl>oxaziridine (5c), a new enantiomerically pure, aprotic oxidizing reagent.Lower stereoselectivities were observed with this reagent for the enantioselective oxidation of 2-substituted 1-tetralone enolates 8 lacking the 8-methoxy group.
View MoreGoldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.
Contact:0086-0576-88551200,88886292 ,88880039
Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY
Contact:0086-0757-85609331
Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Shanghai Norky Pharmaceutical Co., LTD.
website:http://www.norkypharm.com
Contact:86-21-61075300
Address:1165 Jiangning Road, Office 1502, Shanghai, China
Fujian Huitian Biological Pharmacy Co., Ltd.
Contact:0086-598-8300831; 8339920
Address:No.46,Taijiang Road,Sanming City,Fujian,China
Doi:10.1016/S0031-9422(00)97685-4
(1983)Doi:10.1002/adsc.201401026
(2015)Doi:10.1021/om300066v
(2012)Doi:10.1248/cpb.43.1158
(1995)Doi:10.1016/S0040-4039(99)01090-4
(1999)Doi:10.1021/ja808537j
(2009)