Stereoselective Reduction of α,β-Epoxy Ketones into erythro-α,β-Epoxy Alcohols with Sodium Borohydride in the Presence of Calcium Chloride

Article abstract of DOI:10.1246/cl.1992.967

erythro-α,β-Epoxy alcohols were prepared with high steroselectivity by sodium borohydride reduction of the corresponding α,β-epoxy ketones in the presence of calcium chloride or manganese(II) chloride regardless of the substituents on the epoxide ring.