Metabolites of the Marine Sponge Laxosuberites sp.

Article abstract of DOI:10.1021/jo01312a033

The marine sponge Laxosuberites sp. contained a mixture of four 5-alkylpyrrole-2-carboxaldehydes 1, (6'Z)-5-(12'-cyano-6'-dodecenyl)pyrrole-2-carboxaldehyde (2), and (6'Z)-5-(23'-cyano-23'-hydroxy-6'-tricosenyl)pyrrole-2-carboxaldehyde (3).The structures of the metabolites were determined by interpretation of spectral data and by chemical degradation.The cyanohydrin 3 is unusually stable to normal isolation and storage procedures.