Synthesis and DNA binding properties of amide bond-modified analogues related to distamycin

DOI: 10.1016/0040-4039(96)01782-0

Source and publish data:

Tetrahedron Letters p. 7801 - 7804 (1996)

Update date:2022-08-24

Topics:

Authors:

Yamamoto, Yasuo

Kimachi, Tetsutaro

Kanaoka, Yoshitomo

Kato, Satoshi

Bessho, Kiyoshi

Matsumoto, Takuyuki

Kusakabe, Tetsuya

Sugiura, Yukio

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Article abstract of DOI:10.1016/0040-4039(96)01782-0

Novel nitro analogues of distamycin which have trans olefins or α-diketo moiety instead of amide bond were synthesized. Their DNA binding properties studies by ethidium displacement assay and MPE footprinting experiments were also described.

Full text of DOI:10.1016/0040-4039(96)01782-0

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