Archiv der Pharmazie p. 277 - 279 (1989)
Update date:2022-08-15
Topics:
Stamm, Helmut
Speth, Dieter
In ROH/H2SO4 the title compound is exclusively cleaved between N and C-3 yielding predominantly one diastereomer so that only a small portion of ring opening can proceed via a free carbenium ion.Ring opening shows an inverse dependence on the size of R.
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