Preparation and Reactions of 1-(tert-Butyldimethylsilyl)-3-lithioindole. Regioselective Synthesis of 3-Substituted Indoles

DOI: 10.1021/jo00080a004

Source and publish data:

Journal of Organic Chemistry p. 10 - 11 (1994)

Update date:2022-08-11

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Authors:

Amat, Mercedes

Hadida, Sabine

Sathyanarayana, Swargam

Bosch, Joan

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Article abstract of DOI:10.1021/jo00080a004

1-(tert-Butyldimethylsilyl)-3-lithioindole (2) is prepared by metalation of the corresponding 3-bromo derivative 1 and efficiently reacts with electrophiles to give 3-substituted indoles 3 and 4.

Full text of DOI:10.1021/jo00080a004

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