Diterpenes based on the dolabellane skeleton from dictyota dichotoma

Article abstract of DOI:10.1016/0040-4020(80)85055-1

From a variety of Dictyota dichotoma we have isolated, in addition to previously reported dolabellane (6-8) and perhydroazulene diterpenes (9,10), four new diterpenoids (2-5). Their structure have been elucidated by spectral analysis and chemical degradation. All the new dolabellane derivatives possess antimicrobial activity against gram-positive and gram-negative organisms.