A simple method for the preparation of aryl trifluoromethyl ketones

DOI: 10.1055/s-1996-4444

Source and publish data:

Synthesis p. 1093 - 1094 (1996)

Update date:2022-08-11

Topics:

Authors:

Simchen, Gerhard

Schmidt, Andreas

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Article abstract of DOI:10.1055/s-1996-4444

4-Dimethylamino-1-trifluoroacetylpyridinium trifluoroacetate (2) is an effective, easy to handle and stable trifluoroacetylation agent. Aryl trifluormethyl ketones 4 are obtained in good yields by reaction of 2 with aromatic compounds 3 in the presence of aluminum chloride.

Full text of DOI:10.1055/s-1996-4444

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