Bioorganic and Medicinal Chemistry p. 81 - 90 (1996)
Update date:2022-08-30
Topics:
Barraclough, Paul
Bolofo, Mary L.
Giles, Heather
Gillam, Janet
Harris, C. John
Kelly, Michael G.
Leff, Paul
McNeill, Alan
Robertson, Alan D.
Stepney, Ray J.
Whittle, Brendan J. R.
The rationale for investigating conformationally restricted analogues of BW245C as DP-receptor ligands and the syntheses of three such racemic bicyclic imidazolidinone analogues are described. Compounds 7 (BW587C), 8 (BW480C85), and 9 (BW572C85) were found to be potent inhibitors of human platelet aggregation and selective DP-receptor agonists in washed platelet and jugular vein isolated tissue assays.
View More
Contact:86-25-51817806
Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china
website:http://www.eastarchem.com/
Contact:1-800-898-2436
Address:1215 K Street, STE 1700
Tianjin SPHINX SCIENTIFIC LAB.
Contact:+86-022-66211289
Address:Tianda high-tech Park. No.80,the 4th Avenue
Contact:+86-134-5286-9121
Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Wuhan Jadechem International Trade Co.,Ltd.
website:http://www.jadechem-intl.com
Contact:+86-27-83527060
Address:Room 502,Building C11,Software new city No.8,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China
Doi:10.1016/j.jallcom.2015.01.312
(2015)Doi:10.1021/acsmedchemlett.0c00612
(2021)Doi:10.1023/A:1026095431498
(2003)Doi:10.1002/cssc.201500589
(2015)Doi:10.1021/ja01143a538
(1952)Doi:10.1016/S0022-328X(00)00044-9
(2000)
