Synthesis and anti-inflammatory activity of chalcone derivatives

DOI: 10.1016/S0960-894X(98)00179-6

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1169 - 1174 (1998)

Update date:2022-08-23

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Authors:

Herencia, Felipe

Ferrandiz, M. Luisa

Ubeda, Amalia

Dominguez, Jose N.

Charris, Jaime E.

Lobo, Gricela M.

Alcaraz, M. Jose

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Article abstract of DOI:10.1016/S0960-894X(98)00179-6

Chalcones and their derivatives were synthesized and evaluated for their anti-inflammatory activity. In vitro, chalcones 2, 4, 8, 10 and 13 inhibited degranulation and 5-lipoxygenase in human neutrophils, whereas 11 behaved as scavenger of superoxide. Onl

Full text of DOI:10.1016/S0960-894X(98)00179-6

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