Bioorganic and Medicinal Chemistry Letters p. 1169 - 1174 (1998)
Update date:2022-08-23
Topics:
Herencia, Felipe
Ferrandiz, M. Luisa
Ubeda, Amalia
Dominguez, Jose N.
Charris, Jaime E.
Lobo, Gricela M.
Alcaraz, M. Jose
Chalcones and their derivatives were synthesized and evaluated for their anti-inflammatory activity. In vitro, chalcones 2, 4, 8, 10 and 13 inhibited degranulation and 5-lipoxygenase in human neutrophils, whereas 11 behaved as scavenger of superoxide. Onl
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