A PREDOMINATELY ANTI-STEREOSELECTIVE CHIRAL METAL DIRECTED ALDOL CONDENSATION WITH AROMATIC ALDEHYDES

DOI: 10.1016/S0040-4039(01)93794-3

Source and publish data:

Tetrahedron Letters p. 5539 - 5542 (1989)

Update date:2022-08-15

Topics:

Authors:

Pridgen, Lendon N.

Abdel-Magid, A.

Lantos, I.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)93794-3

Chiral haloacetyl oxazolidinones were reacted with aromatic aldehydes via their kinetically generated Z-enolates to yield predominately anti aldol adducts.The reaction is postulated to proceed thru a boat-like transition state.A unique reversal of chirality was observed in using stannous enolates.

Full text of DOI:10.1016/S0040-4039(01)93794-3

Products guided by the article

Product name:syn-(4S,2'R,3'S)-3-(3'-Hydroxy-3'-phenyl-2'-chloro-1'-oxopropyl)-4-(1-methylethyl)-2-oxazolidinone

Cas No:127182-19-8

R&D Labs maybe for 127182-19-8

ANGCHEN BRIGHTCHEM CO., LTD

website:http://www.angchenchem.com

Contact:+86-510-88302099 82327577

Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
changsha chenjin chemical technology co.,LtD(expird)

Contact:86-731-84451263

Address:Room 201/217-218, 101 Jingyuan Electronic Technology Co.,Ltd. Testing Center, No.69, Lufeng Road, High-tech Development Zone, Changsha, China
Changyi Xinxing Technology Development Co., Ltd.

Contact:0086-510-86651065(Time Zone:8),86651656

Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China
Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Shanghai Balmxy Pharmaceutical Co., Ltd

Contact:0086-21-24206007

Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China

Relevant to this article

Donor specificity and regioselectivity in Lipolase mediated acylations of methyl α-d-glucopyranoside by vinyl esters of phenolic acids and their analogues

Doi:10.1016/j.bmcl.2013.07.051
(2013)
Protic ionic liquid [TMG][Ac] as an efficient, homogeneous and recyclable catalyst for one-pot four-component synthesis of 2H-indazolo[2,1-b]phthalazine- triones and dihydro-1H-pyrano[2,3-c]pyrazol-6-ones

Doi:10.1039/c4ra03514c
(2014)
Synthesis and antibacterial evaluation of a novel series of 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles

Doi:10.1002/cbdv.201000241
(2011)
Self-assembly approach toward chiral bimetallic catalysts: Bis-urea-functionalized (Salen)cobalt complexes for the hydrolytic kinetic resolution of epoxides

Doi:10.1002/chem.201002600
(2011)
Synthesis and cytotoxicity of (-)-renieramycin G analogs

Doi:10.1016/j.bmcl.2011.01.025
(2011)
Synthesis and reactions of 2-amino-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-4-phenylpyridine-3- carbonitrile

Doi:10.1002/jhet.5570390211
(2002)

Article Doi