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TYR211, one with ASP170 and one with the hydroxyl at THR208
and the last between the nitrile group and ASP98.
As for RIS (2), it was revealed that it forms nine hydrogen bonds
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enormous potential as drug candidate in the Chagas disease treat-
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10 min and obtained in 100% yield. After a simple filtration the
product was ready for the biological assays, which reiterates its
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