Facile direct conversion of aminoheterocycles to fluoro-heterocycles using t-butylthionitrite or t-butylthionitrate with sodium tetrafluoroborate

Article abstract of DOI:10.1016/S0040-4039(00)89014-0

Amino-nucleic acids and amino-heterocycles reacted readily with t-butylthionitrite or t-butylthionitrate in the presence of anhydrous sodium tetrafluoroborate in neutral and aprotic media to afford the corresponding fluoro-nucleic acids and fluoroheterocycles respectively in good yields.