An enantiocontrolled synthesis of (-)-Swainsonine

Article abstract of DOI:10.1016/0040-4039(95)00920-8

(-)-Swainsonine 1, first isolated from the fungus Rhizoctonia leguminicola, has been sythesized enantioseletively. The key step was the stereoselective iodoamination of trichloro- acetimidate derived from (Z)- olefinic allylic alcohol 7.