((9-Fluorenylmethyl)oxy)carbonyl Amino Acid Chlorides in Solid-Phase Peptide Synthesis

DOI: 10.1021/jo00008a012

Source and publish data:

Journal of Organic Chemistry p. 2635 - 2642 (1991)

Update date:2022-08-11

Topics:

Authors:

Carpino, Louis A.

Chao, Hann Guang

Beyermann, Michael

Bienert, Michael

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Article abstract of DOI:10.1021/jo00008a012

FMOC amino acid chlorides, previously shown to be rapid-acting coupling agents in two-phase systems or in homogeneous solution, did not prove to be directly applicable to solid phase peptide synthesis due to sluggish reactivity.The problem was traced to p

Full text of DOI:10.1021/jo00008a012

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