Chemistry of Heterocyclic Compounds p. 1116 - 1120 (1990)
Update date:2022-08-23
Topics:
Mandur, Adel Hamed Mohamed
Buyanov, V. N.
Zhigachev, V. E.
Kurkovskaya, L. N.
Suvorov, N. N.
The reaction of nitroindoles with chlorosulfonic acid in the presence of sodium sulfate was used to synthesize 4-, 5-, 6-, and 7-nitroindole-3-sulfonyl chlorides.Under the influence of ammonia and several amines these compounds were converted to nitroindole-3-sulfonamides which were reduced with hydrazine hydrate in the presence of Raney nickel to the corresponding amines.
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