A convenient preparation of α-keto esters by the Grignard reaction on N-acylpyrazoles

DOI: 10.3987/COM-98-S24

Source and publish data:

Heterocycles p. 459 - 464 (1998)

Update date:2022-08-24

Topics:

Authors:

Kashima, Choji

Shirahata, Yoshie

Tsukamoto, Yoshihiro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/COM-98-S24

The α-keto esters were prepared by the formation of N-acylpyrazole followed by the appropriate Grignard reaction. These short step reaction conveniently afforded various α-keto esters in good yields.

Full text of DOI:10.3987/COM-98-S24

Products guided by the article

Product name:Ethyl 2-cyclohexyl-2-oxoacetate

Cas No:13275-31-5

R&D Labs maybe for 13275-31-5

Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
Lanzhou huibang biological chemical technology Co., LTD

Contact:0931-7843964

Address:NO.2011,Yannan Road,Chengguan,
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Wuxi Pharma-Trading Import & Export Co.,Ltd.

Contact:+86-510-82304590 82716390

Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
SHUNYUANSHENG BIO-PHARMTECH CO., LTD

website:https://www.whsysbio.com

Contact:--

Address:Building 13, Liandong U Valley-Wuhan Economic Innovation Valley, No. 259, Xingsan Road, Shamao Street, Hannan District, Wuhan City, Hubei Province

Relevant to this article

Porphyrin-linked nitroimidazole antibiotics targeting Porphyromonas gingivalis

Doi:10.1039/b904340c
(2009)
Gating charge recombination rates through dynamic bridges in tetrathiafulvalene-fullerene architectures

Doi:10.1002/anie.201306183
(2013)
Di-tert-butyl ketone hydrazone and di-tert-butyl ketone triphenyl-phosphoranylidenehydrazone

Doi:10.1107/S0108270106008687
(2006)
A vanadium-based chemical oscillator: Identification of chemical species responsible for the redox reaction and construction of a simplified model

Doi:10.1002/ejic.201200148
(2012)
Doi:10.1103/PhysRev.25.452
(1925)
Blue Highly Fluorescent Boranil Derived From Anil Ligand: Synthesis, Characterization, Experimental and Theoretical Evaluation of Solvent Effect on Structures and Photophysical Properties

Doi:10.1002/aoc.5764
(2020)

Article Doi