Diastereoselective Synthesis of Substituted Glutamic Acid Derivatives via Michael Additions of N-glycinates under Solid-Liquid Phase Transfer Catalysis

Article abstract of DOI:10.1021/jo00126a020

Michael additions of the enolates of ethyl and tert-butyl N-glycinates with α,β-unsaturated esters and ketones under solid-liquid phase transfer catalysis allowed for the highly diastereoselective synthesis of substituted glutami