Journal of the Chemical Society. Chemical communications p. 231 - 232 (1995)
Update date:2022-08-17
Topics:
Bentley, Jonathan M.
Wadsworth, Harry J.
Willis, Christine L.
The first examples of the BS- and SE-lactate dehydrogenase catalysed reductions of an α-keto acid incorporating a nitrogen containing function in the side chain are described: (S)- and (R)-benzyloxycarbonylamino-2-hydroxybutanoic acids were prepared in good yield and excellent enantioselectivities and were converted to the (S)- and (R)-3-hydroxypyrrolidin-2-ones respectively.
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